The show was one of the first on British radio to regularly play music from CDs, taking advantage of its FM carriage before Radio 1 had its own higher-quality frequencies. It began its second and most famous run in December 1982, for most of its run in a slot immediately after the Top 40. She had begun The Sunday Request Show in September 1975, originally on Sunday afternoons until the end of 1979. During her tenure, the show moved away from its traditional bias under Harris towards country music, blues rock and progressive rock and embraced popular modern styles such as punk rock and new wave. In 1978, Nightingale became the main presenter of The Old Grey Whistle Test on BBC2 as a replacement for long-time host Bob Harris. In the mid-late 1970s, she presented a Sunday afternoon request show, and in the early 1980s she presented a Friday night show and the non-music-based Radio 1 Mailbag and Talkabout. Later she then hosted the singles review show What's New in the early 1970s before graduating to a late-night progressive rock show, which was simulcast on the Radio 2 FM frequency.

She started at Radio 1 on 5 October 1969 with a Sunday evening show. Her first broadcast on the BBC was on 14 September 1963 as a panellist on Juke Box Jury, and she contributed to Woman's Hour in 1964 and hosted programmes on the BBC Light Programme in 1966. In the 1960s and 1970s, she wrote columns for the Daily Express, the Daily Sketch, Petticoat and Cosmopolitan magazine. After attending Lady Eleanor Holles School, Hampton, southwest London, and the Polytechnic of Central London (now the University of Westminster) School of Journalism, Nightingale began her career as a journalist in Brighton, East Sussex. She was born in 1940 Osterley, as the daughter of Basil John Nightingale (1906-) and his wife, Celia nėe Winter.

Annie nightingale